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KMID : 0964020100100010040
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Journal of the Korean Liver Cancer Study Group
2010 Volume.10 No. 1 p.40 ~ p.43
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A Case of Hepatocellular Carcinoma Exhibited over Partial Response after Hepatic Arterial Infusion Chemotherapy
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Park Chang-Wook
Kwon Young-Lan
Kim Yong-Jin
Kim Yoon-Jung
Seo Hye-Jin
Lee Kyung-In
Kim Eun-Soo
Jang Byoung-Kuk
Chung Woo-Jin
Park Kyung-Sik
Cho Kwang-Bum
Hwang Jae-Seok
Kim Young-Hwan
Kwon Jung-Hyeok
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Abstract
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Hepatocellular carcinoma (HCC) is one of the cancers with poor prognosis. Especially potal vein invasion is a grave prognostic indicator in the setting of HCC. There is currently no effective method for treatment of HCC with portal vein invasion. A 61-year-old female patient was diagnosed a massive HCCs in both hepatic lobe with portal vein thrombosis, based on computed tomography (CT) and increased tumor marker, α-fetoprotein. She was treated with intrahepatic arterial CDDP (10 mg on 1~5 day), 5-FU (250mg on 1~5 day) and leukovorin (12mg on 1~5 day) infusion via percutaneously implantable port system (PIPS) every 3 weeks, totally seven times. The patient was still living 6 months after first hepatic arterial infusion chemotherapy (HAIC) and follow-up CT showed partial response with necrosis of HCCs. We report here a case of advanced HCC with portal vein thrombosis that was effectively treated with HAIC via PIPS.
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KEYWORD
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Hepatocellular carcinoma, Portal vein, thrombosis, Intra-arterial infusion
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